MRI-based biomechanical parameters for carotid artery plaque vulnerability assessment
نویسندگان
چکیده
منابع مشابه
MRI-based biomechanical parameters for carotid artery plaque vulnerability assessment.
Carotid atherosclerotic plaques are a major cause of ischaemic stroke. The biomechanical environment to which the arterial wall and plaque is subjected to plays an important role in the initiation, progression and rupture of carotid plaques. MRI is frequently used to characterize the morphology of a carotid plaque, but new developments in MRI enable more functional assessment of carotid plaques...
متن کاملAssessment of carotid plaque vulnerability using structural and geometrical determinants.
BACKGROUND Because many acute cerebral ischemic events are caused by rupture of vulnerable carotid atheroma and subsequent thrombosis, the present study used both idealized and patient-specific carotid atheromatous plaque models to evaluate the effect of structural determinants on stress distributions within plaque. METHODS AND RESULTS Using a finite element method, structural analysis was pe...
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Image-based computational modeling has been introduced for vulnerable atherosclerotic plaques to identify critical mechanical conditions which may be used for better plaque assessment and rupture predictions. In vivo patient-specific coronary plaque models are lagging due to limitations on non-invasive image resolution, flow data, and vessel material properties. A framework is proposed to combi...
متن کاملMolecular Imaging of Carotid Plaque Vulnerability
Background: Carotid endarterectomy (CEA) has been shown to be beneficial in patients with high-grade symptomatic carotid artery stenosis. Patients with high-grade asymptomatic stenosis may only exceptionally benefit from CEA during periods of increased plaque vulnerability. Imaging modalities to characterize unstable, vulnerable plaques are strongly needed for better risk stratification in thes...
متن کاملMolecular Imaging of Carotid Plaque Vulnerability
Background: Carotid endarterectomy (CEA) has been shown to be beneficial in patients with high-grade symptomatic carotid artery stenosis. Patients with high-grade asymptomatic stenosis may only exceptionally benefit from CEA during periods of increased plaque vulnerability. Imaging modalities to characterize unstable, vulnerable plaques are strongly needed for better risk stratification in thes...
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ژورنال
عنوان ژورنال: Thrombosis and Haemostasis
سال: 2016
ISSN: 0340-6245,2567-689X
DOI: 10.1160/th15-09-0712